Differentiating strong antibiotic producers from weaker ones
An untapped trove of desirable drug-like molecules is hidden in the genomes of Streptomyces bacteria -- the same bacteria responsible...
MEDI CURE
Gene associated with autism linked to itch response, study finds
A pilot study from North Carolina State University has found that a gene associated with autism spectrum disorder (ASD) and...
Model can predict how drug interactions influence antibiotic resistance
Scientists have proposed a modelling framework which could predict how antibiotic resistance will evolve in response to different treatment combinations,...
Scientists model ‘true prevalence’ of COVID-19 throughout pandemic
Government officials and policymakers have tried to use numbers to grasp COVID-19's impact. Figures like the number of hospitalizations or...
Brain’s ‘memory center’ needed to recognize image sequences but not single sights
A new MIT study of how a mammalian brain remembers what it sees shows that while individual images are stored...
What does a virtual roller coaster ride tell us about migraine?
When experiencing the ups and downs of a virtual roller coaster ride, people who get migraine headaches reported more dizziness...
Gamma-secretase ‘buckles up’ to reach its destination
A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to...
Ibrutinib effective treatment for difficult-to-treat forms of hairy cell leukemia, study finds
The oral targeted therapy drug ibrutinib is an effective treatment option for high-risk hairy cell leukemia, according to a new...
Antibiotic prescriptions for kids plummet during pandemic: Study finds declines in prescription drugs dispensed to children during COVID-19, including infection-related medicines and some used for chronic diseases
As children made fewer visits to health facilities and engaged in social distancing and other COVID-19 mitigation measures, a smaller...
Why MS patients develop progressive disability
Did you know multiple sclerosis (MS) means multiple scars? New research shows that the brain and spinal cord scars in...
Red blood cell ‘traffic’ contributes to changes in brain oxygenation
Adequate blood flow supplies the brain with oxygen and nutrients, but the oxygenation tends to fluctuate in a distinct, consistent...
Hope for psychosis sufferers
University of Otago scientists have opened the door to improved treatment of brain dysfunction which causes psychosis. Dr Ryan Ward,...
Scientists provide a more strategic approach to COVID-19 testing
A new study led by the U.S. Geological Survey outlines a means to better estimate COVID-19 occurrence and trends in...
Newfound human brain cell type helps center people in mental maps: Experiments in virtual reality shed light on the cellular mechanisms underlying navigation and memory in humans
A previously unknown kind of human brain cell appears to help people center themselves in their personal maps of the...
Metal-based molecules show promise against the build-up of Alzheimer’s peptides
In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer's...
Fungi that live in the gut influence health and disease: Vaccines that balance gut microbial communities may one day be used to improve gastrointestinal health
Bacteria's role in gut health has received a lot of attention in recent years. But new research led by scientists...
Magnetic field from MRI affects focused-ultrasound-mediated blood-brain barrier
MRI-guided focused ultrasound combined with microbubbles can open the blood-brain barrier (BBB) and allow therapeutic drugs to reach the diseased...
A step toward advancing precision hormone therapies to reduce Alzheimer’s risk
A new University of Arizona Health Sciences study found women on hormone therapy were up to 58% less likely to...
Mucus and mucins may become the medicine of the future
Many people instinctively associate mucus with something disgusting, but in fact, it has incredibly many valuable functions for our health....
Air pollution during pregnancy may affect growth of newborn babies
According to studies in recent years, air pollution affects the thyroid. Thyroid hormones are essential for regulating fetal growth and...
Vaccines grown in eggs induce antibody response against an egg-associated glycan, study finds
Over years of studying antibody responses against the flu in the Wilson lab at the University of Chicago, researchers kept...
Employed individuals more likely to contract the flu, study shows
A University of Arkansas researcher and international colleagues found that employed individuals, on average, are 35.3% more likely to be...
Thermal imaging offers early alert for chronic wound care: Textural analysis of thermal images of venous leg ulcers can detect if a wound needs extra care
New research shows thermal imaging techniques can predict whether a wound needs extra management, offering an early alert system to...
Drug relieves persistent daydreaming, fatigue, and brain sluggishness in adults with ADHD
Tests of a drug known to stimulate brain activity have shown early success in reducing symptoms of sluggish cognitive tempo...
Potential new CAR-T cell therapy for multiple myeloma
Researchers at Mayo Clinic Cancer Center are studying a potential new chimeric antigen receptor-T cell therapy (CAR-T cell therapy) treatment...
Glial cells help mitigate neurological damage in Huntington’s disease
The brain is not a passive recipient of injury or disease. Research has shown that when neurons die and disrupt...
Abnormal response to cellular stress is associated with Huntington’s disease
A new University of California, Irvine-led study finds that the persistence of a marker of chronic cellular stress, previously associated...
Study reveals agriculture-related injuries more numerous than previously known
A new study by Penn State researchers, who looked at emergency room admissions across the U.S. over a recent five-year...
Companies who pay scant attention to workers’ psychological health leave employees at higher risk of depression, research finds
A year-long Australian population study has found that full time workers employed by organisations that fail to prioritise their employees'...
Self-reported declines in cognition may be linked to changes in brain connectivity
Jessica Damoiseaux, Ph.D., an associate professor with the Institute of Gerontology at Wayne State University, recently published the results of...
Common antibiotic found useful in accelerating recovery in tuberculosis patients
Globally, an estimated 10 million people develop tuberculosis (TB) each year and the disease remains a leading cause of death...
New evidence to battle drug price increases
Two recent studies led by researchers from the University of Minnesota Medical School add new evidence to the impact of...
Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?
Will a reduction in tau protein in brain neurons protect against Parkinson's disease and Lewy body dementias? A new study,...
Targeting cellular response to SARS-CoV-2 holds promise as new way to fight infection
When a person is infected with SARS-CoV-2, the virus that causes COVID-19, it invades their cells and uses them to...
Induced hypothermia after cardiac arrest did not improve survival
Since 2005, the guidelines for the care of unconscious cardiac arrest patients have been to cool the body temperature down...
Targeted drug found effective in thwarting pancreatic tumors
Pancreatic cancer is an aggressive disease in which malignant cells form in the tissues of the pancreas, a long and...
Potential new treatment target for Alzheimer’s disease
Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about...
AI predicts how patients with viral infections, including COVID-19, will fare
Researchers at University of California San Diego School of Medicine used an artificial intelligence (AI) algorithm to sift through terabytes...
Study examines the effects of COVID-19 on human kidney cells
Researchers have studied human kidney cells in the lab to examine the effects of COVID-19 on kidney health. The findings...
Predisposition to addiction may be genetic, study finds
People who have a high sensation-seeking personality trait may be more likely to develop an addiction to cocaine, according to...
UIC research paves way for next-generation of crystalline material screening devices
Researchers at the University of Illinois Chicago have developed a novel continuous-flow microfluidic device that may help scientists and pharmaceutical...
First glimpse of brains retrieving mistaken memories observed
Scientists have observed for the first time what it looks like in the key memory region of the brain when...
Defying body clock linked to depression and lower wellbeing
People whose sleep pattern goes against their natural body clock are more likely to have depression and lower levels of...
Heavy water makes biological clocks tick more slowly
They recently published their findings in the journal Advanced Materials. Cells are not only our biological building blocks, but also...
Lessons from the last pandemic point the way toward universal flu vaccines: Strong immune responses to unchanging, conserved parts of the 2009 H1N1 pandemic flu virus suggest strategies for effective universal vaccines
A new study from the University of Chicago and Scripps Research Institute shows that during the last great pandemic --...
Genetic base editing treats sickle cell disease in mice: Converting a pathogenic hemoglobin gene to a benign variant enables healthy blood cell production in an animal model of sickle cell disease
Sickle cell disease (SCD) is the most common deadly genetic disorder, affecting more than 300,000 newborns worldwide each year. It...
Role of sleep-related brain activity in clearing toxic proteins and preventing Alzheimer’s disease
Evidence of sleep-dependent low-frequency (PLOS Biology by Xiao Liu and colleagues at The Pennsylvania State University. This neuronal activity was...
Scientists identify mechanism linking traumatic brain injury to neurodegenerative disease
Scientists have revealed a potential mechanism for how traumatic brain injury leads to neurodegenerative diseases, according to a study in...
Changes in how cholesterol breaks down in the body may accelerate progression of dementia: Study suggests that some cholesterol medications may impact signaling pathways in the brain, particularly in men
The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimer's disease and...
Fight against antibiotic-resistant bacteria has a glowing new weapon
In the perpetual arms races between bacteria and human-made antibiotics, there is a new tool to give human medicine the...
The hunt for drugs to neutralize critical enzymes: Scientists explore racemases and propose strategies for finding drugs that target these important enzymes
Scientists from the UK's University of Bath explore racemases -- an important type of enzyme that is linked to certain...
Flu fighter: Nanoparticle-based vaccine effective in preclinical trials: The vaccine, made of disease-fighting proteins, could boost efficacy, accelerate production of seasonal flu vaccines
An experimental flu vaccine consisting of billions of tiny spherical sacs that carry infection-fighting proteins throughout the body has proven...
Longstanding fallopian tube transport debate solved
Today, The Lundquist Institute announced that Wei Yan, MD, PhD, and his research group have solved a longstanding mystery and...
Simple diagnostic tool predicts individual risk of Alzheimer’s
Researchers at Lund University in Sweden have developed an algorithm that combines data from a simple blood test and brief...
